Antimicrobial Stewardship

What is Antimicrobial Resistance (AMR) ?

AMR occurs when bacteria, viruses, fungi and parasites change over time and no longer respond to medicines making infections harder to treat and increasing the risk of disease spread, severe illness and death. As a result, the medicines become ineffective and infections persist in the body, increasing the risk of spread to others.

How does Antibiotic resistance occur ?

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Source: CDC

The development of resistant bacteria is a natural phenomenon that is exacerbated and accelerated by the inappropriate use of antibiotics in the fields of human and animal health and the inadequate infection control.

The cost is high, If we do not address AMR now

Every 45 seconds someone dies from an infection caused by a resistant bacteria

Source: WHO (October 27th)

Act now: It’s the only way we will reduce the threat of resistance

Antimicrobial Stewardship (AMS) is critical to fight the AMR crisis. AMS programs help fight antimicrobial resistance by providing a framework for responsible antibiotics prescribing and use, optimizing individual therapy, helping reduce the spread of resistance and raising awareness & education.

bioMérieux: your partner of choice on AMS

Put diagnostics at the heart of Antimicrobial Stewardship to drive informed therapy decisions.

bioMérieux has the most comprehensive solutions on the market all along the patient pathway:

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Product availability varies by country. Consult your bioMérieux sales representative.

Our complete AMS solution encompasses more than just traditional state-of-the-art lab technology. Because at bioMérieux we fully understand your antimicrobial stewardship (AMS) needs our offer translates into 4 key areas where we help hospitals and labs worldwide evolve to suit today’s needs and tomorrow’s concerns:

How can we help the lab?

We accompany you with a tailored offer to leverage your diagnostic expertise and ensure clinicians optimize therapy sooner. bioMérieux can support you to provide relevant laboratory data to optimize antibiotic therapy

ANTIBIOTIC THERAPY INITIATION

	MYLA Provide up-to-date Antibiogram Reports to help empiric therapy decisions
	BIOMERIEUX LAB CONSULTANCY Reduce time-to-results by streaming processes and optimizing resource use
	VIDAS BRAHMS PCT Evaluate whether to start antibiotic therapy and establish a baseline for monitoring patient response to antibiotic therapy
	PREVI COLOR GRAM Guide treatment options through rapid standardized Gram stain results
	BIOFIRE FILMARRAY SYSTEMS Reduce time to optimal therapy, shorten patient stay and avoid unnecessary testing

ANTIBIOTIC THERAPY OPTIMIZATION

	BACT/ALERT VIRTUO Earlier optimization of antibiotic therapy and improved blood culture monitoring practices from an even faster and integrated time to result
	BIOFIRE BCID2 PANEL Detect 43 targets including 10 AMR genes in about 1 hour to help optimize patient treatment decision & improve outcomes
	WASP & WASPLab Flexible automated specimen processing and reading solution for a faster time to result with a focus only on specimens with clinical interest
	VITEK MS PRIME Maximize daily routine workflow with enhanced productivity for faster time to reported results to positively impact patient care
	VITEK 2 Optimize therapy decisions with same-day expertized AST results
	CHROMID range One-step isolation and direct identification of major pathogens responsible for infection
	ETEST Extensive MIC information of new and existing antibiotics to further optimize patient therapy
	RAPIDEC CARBA NP Detection and confirmation of carbapenemase-producing Gram-negative bacilli
	VIDAS BRAHMS PCT Monitor patient response to antibiotic therapy
	MYLA Optimize therapy with value-added comprehensive results and streamlined workflow
	BIOMERIEUX EPISEQ CS Keep track of resistance and virulence genes profiles within hospital acquired infections
	CDSS-AMS Optimize antimicrobial prescription with decision-support
	CDSS-HAI Decision support to help prevent nosocomial infections

ANTIBIOTIC THERAPY DISCONTINUATION

VIDAS BRAHMS PCT Support discontinuation decisions

How can we help the AMS Committee?

bioMérieux can support you all along your AMS journey with a dedicated offer for AMS Committee members to start an AMS Program or help you to go to the next level and encourage prescription guideline compliance. Here’s what you can do:

AMS PROGRAM INITIATION

	MYLA Aggregate data for resistance patterns within organism occurrence and cumulative antibiogram
	MEDICAL EDUCATION MODULES Showcase the medical and economic value of in vitro diagnostics to support AMS to clinicians and healthcare professionals in collaboration with the microbiology laboratory

AMS PROGRAM IMPROVEMENT

	MYLA Aggregate data efficiently to capitalize on hospital resistance within microbiology data and antibiotic consumption data
	MEDICAL EDUCATION MODULES Provide Medical Education Modules on AMS actions/interventions to support AMS to clinicians and healthcare professionals in collaboration with the microbiology laboratory

AMS INITIATIVES COMPLIANCE

	CDSS-AMS Decision support to optimize antimicrobial prescription
	VITEK 2 Selective susceptibility reporting based on rules engine taking into consideration site specificities
	MYLA Complement VITEK 2 rules engine with patient demographic and complementary testing activities information

Additional Resources on Antimicrobial Stewardship

Check out our:

References

• Review on Antimicrobial Resistance. Antimicrobial resistance: Tackling a crisis for the health and wealth of nations.
  
  Available at https://amr-review.org/sites/default/files/AMR Review Paper - Tackling a crisis for the health and wealth of nations_1.pdf.
• WHO report on Antimicrobial resistance crisis.
  
  Available at https://www.who.int/news/item/29-04-2019-new-report-calls-for-urgent-action-to-avert-antimicrobial-resistance-crisis

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