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ARGENE® SOLUTION

Complete molecular biology solution for transplant testing needs

The ARGENE® SOLUTION covers all transplant testing needs and creates seamless lab workflow. Discover the Power of One for transplant testing needs.

  • Automate your sample extraction from a wide variety of sample types
  • Automate your PCR setup for improved standardization
  • Automate your testing for transplant patients with ready to use Real-Time PCR assays
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High quality diagnostic testing is important for transplant patients at every step of the process. It is used to help assess donor-recipient compatibility, prevent and/or control infection, and adapt immunosuppressive therapy as necessary. Transplant patient care is complicated – patients are at risk for a wide range of viral infections, and various different sample types may be used. The ARGENE® SOLUTION was designed to provide the Power of One to cut down on complication and meet transplant testing needs. Reliable, same-day results support clinicians make better treatment decisions for more successful recoveries for transplant patients.

Maximize your efficiency

The ARGENE® SOLUTION brings together a single standardized workflow, reliable extraction reagents and real-time PCR assays. This allows you to better organize your daily routine to deliver accurate same day results – contributing to positive outcomes for transplant patients.  

The Power of One:

  • One single standardized extraction workflow for all samples
  • One unique set of extraction reagents for all sample types
  • One common internal control allowing multi-target detection on one single eluate
  • One harmonized pipetting and PCR protocol

 

Leverage true flexibility

The ARGENE® SOLUTION offers you a unique modular system approach that allows you to better manage your daily transplant testing routine through flexible batching.

  • Mixing various sample types in one extraction run using one single standardized workflow for all samples
  • Flexible input/elution volume per sample within the same extraction run
  • Primary and lysed samples managed within the same extraction run
  • Multiple target detection from one extracted sample
  • Multiple validated samples per PCR target (whole blood, plasma, BAL, stool, urine… depending of the parameter)
  • ARGENE® ready-to-use assays validated on most common Real-Time PCR systems available on the market
  • Comprehensive menu for viral infections monitoring for transplanted  patients
  • Consolidated solution with broader menu for respiratory and central nervous system infections

Results you can trust

The ARGENE® SOLUTION combines proven quality technologies and products.

  • Rely on easyMAG® know-how
    • Recognized extraction quality
    • BOOM technology and easyMAG® reagents
  • Best-in-class ARGENE® CE-IVD Real-Time PCR transplant menu for qualitative and quantitative applications
  • Automate your PCR result interpretation with Results ManagerTM software, according to your defined rules
  • Paperless data transfer process thanks to ARGENE® CONNECT software: full connectivity between LIS, EMAG®, NUCLISENS® easyMAG®, ESTREAM®, most common Real-Time PCR platforms and Results ManagerTM
  • Remote support and troubleshooting through a secure connection thanks to VILINK® software


 

Equipments

Sample preparation

EMAG® specifications
Dimensions Benchtop format : H 111 cm x W 142 cm x D 80 cm
Cabinet format : H 181 cm x W 142 cm x D 80 cm
Weight Benchtop format: 265 Kg
Cabinet format:  330 Kg
Sample number 1 to 48 reactions per run
Sample volume 10 to 1000µl per sample
Elution volume 25 µl to 200µl (5µl increment)
Run time Approx. 90 minutes for 48 samples
LIS connectivity Yes
UV Lamp Yes
HEPA Filter Yes
IVD compliance CE marked according to IVD directive 98/79/EC

 

NUCLISENS® easyMAG® specifications
Dimensions Benchtop format : H 53 cm x W 100 cm x D 65 cm
Weight 125 kg
Sample number 1 to 24 reactions per run
Sample volume 10 to 1000µl per sample
Elution volume 25 µl to 110µl (5µl increment)
Run time Approx. 60 minutes for 24 samples
LIS connectivity Yes
IVD compliance CE marked according to IVD directive 98/79/EC

PCR setup

ESTREAM® specifications
Dimensions H 47 cm x W 60 cm x D 51.5 cm
Weight 45 kg
Deck Capacity 9x microplates full positions and 3 reagent racks positions
Pipetting head 200 µl single channel head
Run time Approx. 35 minutes for 96 well plate setup
LIS connectivity Yes
UV Lamp Yes
HEPA Filter Yes

Reagents

Sample preparation

Product Name Reference
NUCLISENS® easyMAG® Wash Buffer 1 Ref. 280130
NUCLISENS® easyMAG® Wash Buffer 2 Ref. 280131
NUCLISENS® easyMAG® Wash Buffer 3 Ref. 280132
NUCLISENS® easyMAG® Silica Ref. 280133
NUCLISENS® easyMAG® Lysis Buffer Ref. 280134
NUCLISENS® easyMAG® disposables Ref. 280135

Real-Time PCR assays

Product Name Reference
ADENOVIRUS R-GENE® Ref. 69-010B
BK Virus R-GENE® Ref. 69-013B
HHV6 R-GENE® Ref. 69-006B
CMV R-GENE® Ref. 69-003B
EBV R-GENE® Ref. 69-002B
Parvovirus B19 R-GENE® Ref. 69-019B
HSV1&2 VZV R-GENE® Ref.69-014B
HSV1 HSV2 R-GENE® Ref. 71-021
VZV R-GENE® Ref . 71-022

Please contact your local bioMérieux representative for product availability in your country.

CHU Grenoble Testimonial

Discover ARGENE® SOLUTION in video

ARGENE® SOLUTION - I am One

ARGENE® SOLUTION - What you do?

 

Please consult your local bioMérieux representative for product availability in your country

Pioneering diagnostics