All products for:ARGENE®COVID-19 Enterovirus Respiratory viruses Molecular diagnostics Real-time amplification Centralized testing Respiratory Tract Infections

ARGENE^® Respiratory range

Real-time PCR detection kits for viral respiratory diseases

Complete and ready-to-use kits
Validated on major extraction and amplification platforms

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ARGENE^® Respiratory advantages

Modular multiplex solution
- Targeted diagnostic strategy with an “à la carte” menu
- Choose which pathogens to test depending on the season
- Allow the diagnosis of co-infections

Sensitive and reproducible
- Reliable detection of infectious agents involved in viral respiratory diseases
- All controls included (positive control, negative control, internal control)
- Internal control is an endogenous internal control to check for extraction/amplification process and sample quality
Flexible
- Validated for use with various upper and lower respiratory samples
- For use on manual workflow or on automated ARGENE^® SOLUTION workflow
- Validated for use on major extraction and amplification platforms

Everything you need in one kit

R-GENE^® kits include all necessary reagents:

• Ready-to-use amplification premix (including Taq polymerase)

• Reverse transcriptase

• Positive control

• Negative control

Easy procedure

Using R-GENE^® assay is easy.

	SARS-COV-2/FLUA/FLUB/RSV R-GENE^®	COVID-19R-GENE^®	RHINO&EV/CcR-GENE^®
Ordering information	Reference: 424433 Designation: SARS-COV-2/FLUA/FLUB/RSV R-GENE^®	Reference: 424017 Designation: COVID-19 R-GENE^®	Reference: 71-042 Designation: Rhino&EV/Cc R-GENE^®
Test principle		Real Time PCR Detection kit
Technology		Real-Time PCR / 5’ nuclease technology
PCR design	5-PLEX PCR 1. SARS-CoV-2 2. Influenza A 3. Influenza B 4. RSV 5. Endogenous Internal Control	2-PLEX PCR 1. SARS-CoV-2 2. Endogenous Internal Control	2-PLEX PCR 1. Rhino&EV 2. Endogenous Internal Control
Targeted genes	SARS-CoV-2: N & RdRp genes Influenza A: M gene Influenza B: M gene RSV: M gene Endogenous Internal Control: HPRT1 gene	SARS-CoV-2: N & RdRp genes Endogenous Internal Control: HPRT1 gene	Rhinovirus A/B/C: non coding 5' region Enterovirus A/B/C/D: non coding 5' region Endogenous Internal Control: HPRT1 gene
Specimens	Nasopharyngeal Swab	Nasopharyngeal Swab Saliva	Nasopharyngeal Swab Nasopharyngeal Aspirate Bronchoalveolar Lavage
Extraction platforms	• EMAG^® • NUCLISENS® easyMAG^® • QIAsymphony SP • MagNA Pure 96 • MGISP 960	• EMAG^® • NUCLISENS® easyMAG^® • QIAsymphony SP • MagNA Pure 96 • MGISP 960	• EMAG^® • NUCLISENS^® easyMAG^® • QIAsymphony SP
Amplification platforms	• QuantStudio 5 • QuantStudio 5 Dx • CFX96 • CFX Opus 96	• QuantStudio 5 • QuantStudio 5 Dx • CFX96 • CFX Opus 96 • 7500 Fast • 7500 Fast Dx • LightCycler 480 (System II)	• QuantStudio 5 • QuantStudio 5 Dx • CFX96 • CFX Opus 96 • 7500 Fast • 7500 Fast Dx • LightCycler 480 (System II)
Kit content		All included (amplification premix, reverse transcriptase, positive control, negative control)
Controls included		Positive Control, Negative Control, Endogenous Internal Control
Number of tests	96 tests	96 tests	60 tests
Storage conditions		-15°C / -31°C
Status	For In Vitro Diagnostic use (CE marked under EU regulation 2017/746)	For In Vitro Diagnostic use (CE marked under EU directive 98/79/CE)	For In Vitro Diagnostic use (CE marked under EU regulation 2017/746)

Fast facts on Respiratory Pathogens

What are Respiratory Pathogens?

The vast majority of respiratory illnesses are caused by viruses and bacteria. In both children and adults, acute respiratory infections (ARI) are most frequently due to infections with Influenza A and B viruses, Parainfluenza viruses 1, 2 and 3, Respiratory Syncytial Virus (RSV A and B), Adenoviruses and Rhinoviruses. Others pathogens such as Coronaviruses, Bocaviruses, Enteroviruses, Parainfluenza 4, human Metapneumovirus, Mycoplasma pneumonia, Chlamydia pneumoniae, Legionella pneumophila, Bordetella pertussis and Bordetella parapertussis also infect the respiratory tract and can cause various diseases from mild self-limiting upper respiratory infections to potentially threatening pneumonia.

Who is most at risk?

Anyone can become infected and ill with these respiratory pathogens. However, young children, the elderly, immunocompromised or weakened individuals (including those with chronic disease, cancer, or in intensive care) are most likely to suffer serious and potentially life-threatening pneumopathies.

What are the benefits of Respiratory pathogens molecular testing?

Clinical symptoms for different respiratory illnesses are similar so in vitro diagnostic molecular methods are necessary to determine the causative agents. Early, rapid and specific detection of the virus or bacteria involved using real-time PCR methods is essential to provide patient-tailored therapy for better outcomes. An accurate diagnosis will also help to control outbreaks, reduce potential antibiotic resistance and facilitate a more rapid patient recovery.