BIONEXIA® Noro/Rota-Adeno

Rapid 3-in-1 detection of main gastroenteritis viruses

BIONEXIA® Noro/Rota-Adeno is a rapid test able to detect specific antigens in human stool. It is an accurate first-line answer to help contain outbreaks, avoid inappropriate antibiotic therapy, and reduce children mortality in low-income countries.

  • Simple and safe procedure
  • Ready-to-use stool extraction device included in the kit
  • Results in just 10 minutes for optimized patient management
  • State-of-the-art performances 
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Acute gastroenteritis (GE) is the second leading cause of morbidity and mortality worldwide1,2,3, often provoked by Norovirus, Rotavirus and Adenovirus in both children and adults. Rotavirus A is the first cause of diarrhea in children under 2 years old4, and 73% of GE outbreaks in the elderly are caused by Norovirus5.

Screening efforts must focus particularly on enteric viruses as they are extremely contagious6. Rapid isolation of infected patients is essential to limit outbreaks, especially in community settings. It is therefore important to be able to identify the origin of the disease as soon as possible. Differentiating a bacterial from a viral gastroenteritis will also avoid unnecessary antibiotic prescription.

bioMérieux offers BIONEXIA® Noro/Rota-Adeno: a qualitative immunochromatographic test for the rapid detection and differentiation of Norovirus, Rotavirus and Adenovirus in human stool specimens. It can be used in labs or during medical consultations for optimized patient management.

Simple and safe procedure

Reduced handlings for optimized workflow

  • Only 1 stool extract for simultaneous detection of 3 viruses
  • Ready-to-use stool extraction device: the collection tube already contains the buffer

Ease of use for universal practice

  • Simple steps:
    • Collect and extract the stool
    • Apply 2 drops of sample to each of the 2 wells on the cassette

  • Specific protocol for use with stool samples collected in modified (semi-solid) Cary-Blair transport tube
  • Adapted to urgent diagnosis: results in just 10 minutes
  • Test validated for near-patient testing

Safe procedure:

  • Convenient extraction vial ensures limited contact with stool sample

bioMérieux’s solution for the diagnosis of gastroenteritis

How to diagnose gastroenteritis?

* STEC = Shiga Toxin Escherichia Coli

Adapted from UK Standards for Microbiology Investigations, Syndromic S7. 2013

According to international guidelines for the management of gastroenteritis and diarrhea7, Noro/Rota-Adeno antigen tests are mainly recommended for use as a first-line test for children and suspicion of outbreaks in communities.

In addition to BIONEXIA® Noro/Rota-Adeno, bioMérieux offers a complete solution for the diagnosis of gastroenteritis:

Rapid diagnosis of viral gastroenteritis

Antigen detection in stool

Results within 10 minutes

BIONEXIA® Noro/Rota-Adeno

BIONEXIA® Rota-Adeno

Ref. 415089

Ref. 418227

Automated stool detection of C. difficile GDH (results within 50 minutes) and toxin A & B (results witin 75 minutes)

VIDAS® C. difficile GDH

VIDAS® C. difficile Toxin A & B

Ref. 30125

Ref. 30118

Automated multiplex PCR system for syndromic testing Results within 65 minutes

FilmArray® Gastrointestinal (GI) panel

Simultaneous detection of 22 pathogens
(13 bacteria, 5 viruses, 4 parasites).

Ref. RFIT-ASY-0116 / RFIT-ASY-0104

Complete the picture with flexible ID/AST*

Collection, transport & preservation system

FecalSwabTM: 2 mL of modified Cary-Blair medium + one regular flocked swab compatible with BIONEXIA® and FilmArray®

Ref. 470CE.A

Chromogenic culture media

CHROMID® Salmonella / Hektoen

CHROMID® Salmonella Elite

CHROMID® C. difficile CASATM (Campylobacter)


Ref. 43465

Ref. 412108

Ref. 43871

Ref. AEB520270

Ref 43762

Standard and selective culture media

Mac Conkey agar (Enterobacteriaceae)

Hektoen agar

Yersinia CIN agar

Campylosel agar

SS agar (Salmonella Shigella)

SMAC CT agar

Ref. 43141 & 43149

Ref. 43111 & 43119

Ref. 43421 & 43209

Ref. 43361

Ref. 43091 & 43099

Ref. 43391

Automated ID/AST and Advanced Expert SystemTM




Manual ID/AST

API® ID 32




* ID/AST = Identification and Antibiotic Susceptibility Testing

Contact your local representative for availability in your country.



Guarino et al. J Pediatr Gastroenterol Nutr, Vol. 46, No. 5, 2008

2 Kotloff et al. Lancet. 382(9888):209-22,2013

3 Li et al. Clin Microbial Infect. Vol 22, Issue 4, April 2016

4 UK Standards for Microbiology Investigations, Bacteriology B30, 2014

5 Barret et al. Euro Surveill.;19(29), 2014

6 Tam et al. Gut. 61(1): 69–77, 2012

7 UK Standards for Microbiology Investigations, Syndromic S7. 2013

BIONEXIA® Noro/Rota-Adeno


Dual strip cassette


415 089

Contents of the kit 

Each kit includes:

  • 20 individually-sealed pouches each containing a test cassette, a pipette and a desiccant
  • 20 stool extraction vials containing specimen dilution buffer
  • Package insert

Quick user guide printed on the box

Sample type


Sample volume

1-2 g

Liquid stools : 1-2 mL



Positive % agreement= 97.6% vs  ICT

Negative % agreement=  97.5% vs ICT

Positive % agreement= 89.9% vs  RT-PCR

Negative % agreement=  97.3% vs RT-PCR



Positive % agreement= 80.7 % vs  ICT

Negative % agreement=  100 % vs ICT



Positive % agreement= 72.0 % vs  ICT

Negative % agreement=  99.6 % vs ICT

Time to result

10 minutes
The test result is stable for 5 minutes.

Storage temperature

2 – 30°C

Shelf life

24 months from date of manufacturing

* See package insert for further details.


Kits are for use by healthcare professionals in laboratories, and for near-patient testing as part of medical consultations.

Consult your local bioMérieux representative for product availability in your country.

Please consult your local bioMérieux representative for product availability in your country

Pioneering diagnostics