CHROMID® Colistin R Agar

Chromogenic medium for the screening of colistin resistance

This selective chromogenic agar is the first to be validated for the screening of Enterobacteriaceae colistin-resistant micro-organisms in clinical and veterinary samples: E.coli, K.pneumoniae, Enterobacter spp and Salmonella spp.

  • Results in 18-24 hours after 4-5 hour enrichment
  • Facilitates identification of colistin resistance carriers
  • 88.1% sensitivity to report results with confidence
  • Ref: 421170

Sensitivity and ease of use - A global approach to human and animal health - Leading the charge on Multi-Drug Resistant Organisms

Colistin is a polymyxin, with broad-spectrum activity against Gram-negative bacteria. Used in agriculture to control infection in pigs and cattle, it has recently been re-introduced as a last-resort option for humans to treat certain antibiotic-resistant strains. Transferable Colistin resistance, via the plasmid-borne mcr-1 gene, is now emerging in both humans and animals, compromising this antibiotic’s clinical utility1,2. Its continued spread may lead to the global presence of pan-drug-resistant pathogens1,2. Efficient Colistin resistance screening can help prevent that spread and preserve polymyxins for future generations. 

Sensitivity and ease of use

CHROMID® Colistin R is the first validated chromogenic medium to enable the isolation and screening of acquired Colistin-resistant Enterobacteriaceae : E.coli, K.pneumoniae, Salmonella.

It facilitates tracking of Colistin resistance in both asymptomatic carriage and infected patients to ensure earlier appropriate antimicrobial therapy:

  • After 4/5 hour enrichment using BHI broth, results in 18/24-hours for timely detection
  • Easy to use for clear-cut detection of mixed cultures
  • Sensitive method for increased result confidence3
  • Validated for use with stools and rectal swabs

Identification is easy to perform: CHROMID® Colistin R is compatible with VITEK® 2, VITEK® MS.

A global approach to human and animal health

Just as micro-organisms know no borders, there are no borders between human and animal health. In line with the FAO-OIE-WHO initiative to coordinate global activities and address health risks at the animal-human-ecosystems interfaces4, bioMérieux is developing a “One Health” approach in the development of new products. Mobile Colistin resistance is a huge threat for both human and animal health. That’s why CHROMID® Colistin R was designed and validated for use on both clinical and veterinary samples.

Leading the charge on Multi-Drug Resistant Organisms

With 50 years of expertise in infectious diseases, bioMérieux is a pioneer in the development of antibiotic resistance detection and susceptibility testing. Fighting antimicrobial resistance is one of our priorities.

CHROMID® Colistin R is part of our extensive multi-drug-resistant organism screening range, which also includes CHROMID® MRSA SMART, CHROMID® VRE, CHROMID® ESBL, CHROMID® CARBA SMART, CHROMID® CARBA and CHROMID® OXA-48. The CHROMID® range of culture media helps make it possible to provide targeted, adjusted and specific therapies for improved patient outcome, while preventing the spread of antibiotic resistance worldwide.

References:

1 .   Caniaux I, et al. Eur J Clin Microbiol Infect Dis. 2017 Mar;36(3):415-420.

2.    Liu YY, et al. Lancet Infect Dis, 2016; 16(2):161-8.

3.    Roche JM, et al. Poster presented at ECCMID 2017.

4.    Food and Agriculture Organization (FAO) - World Organisation for Animal Health (OIE) - World Health Organization (WHO). A Tripartite Concept Note. April 2010.
http://www.who.int/influenza/resources/documents/tripartite_concept_note_hanoi_042011_en.pdf

CHROMID® Colistin R Agar

 

Ref. 421170

20 plates x 90 mm

CE-marked product

Please contact your local bioMérieux representative for product availability in your country.

 

Please consult your local bioMérieux representative for product availability in your country

Pioneering diagnostics