Chromogenic media for ESBL screening

Help promote effective infection control through reliable screening* of Extended-Spectrum Beta Lactamase-producing Enterobacterales (ESBL) with CHROMID® ESBL selective chromogenic media.

  • ESBL screening in 18-24 hours
  • Validated on variety of specimens: rectal swabs, urine, respiratory secretions and others
  • Patented substrate and antibiotic mix enables direct identification

*ESBL production must be confirmed

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Today’s healthcare environment is more complex and challenging than ever before, with multi-drug resistant organisms (MDRO) and related risk of healthcare associated infection (HAI) outbreaks among the most critical concerns. Many healthcare associated infections are caused by Enterobacterales. When these bacteria produce extended-spectrum β-lactamase (ESBL) enzymes, they become resistant to our most common antibiotics, and are particularly likely to lead to morbidity and mortality from bloodstream infections. ESBL-producing enterobacteriaceae are recognized worldwide as nosocomial pathogens of major importance, listed as a “serious threat” by the Centers for Disease Control1. Rapid, reliable screening of ESBL is essential to improved patient care, infection control and outbreak management.

1) Antibiotic Resistance Threats in the United States, CDC 2019

Support effective infection control

CHROMID® ESBL is part of the bioMérieux SMART range of media, developed specifically to address the challenges of MDRO and HAI. CHROMID® ESBL is based on an agar with a patented mixture of antibiotics designed specifically to enable the selective growth of ESBL-producing enterobacterales* and chromogenic substrates for the direct identification of the most frequently encountered ESBL-producing enterobacterales. CHROMID® ESBL provides results in 18-24 hours, enabling timely delivery of results to support effective infection control measures for better patient outcomes and cost-containment thanks to faster responses.


CHROMID® ESBL provides rapid, easy-to-read results

* ESBL production must be confirmed by additional tests

Rapid, sensitive and specific

CHROMID® ESBL provides high sensitivity thanks to the inclusion of the antibiotic Cefpodoxime, the marker of choice for this resistance mechanism. Time-to-results is also shortened by a high level of specificity and the reduced number of confirmation tests needed. After optimal incubation of 18 hours, you’ll be confident in the reliability of easy-to-read results with the specific coloration enhanced by chromogenic media:

  • Escherichia coli: pink to burgundy coloration of ß-glucuronidase-producing colonies
  • KESC (Klebsiella, Enterobacter, Serratia, Citrobacter): green/blue to browny-green coloration of ß-glucosidase-producing colonies
  • Proteeae (Proteus, Providencia, Moraganella): dark to light brown coloration of deaminase-expressing strains.

Compatibility assured

Need to know if CHROMID® ESBL and another product are compatible? You can easily access this information through a validated Certificate of Compatibility which clearly shows product compatibility with complementary instruments and reagents.

  • Clear compatibility easily assured
  • Meet your accreditation requirements with ease
  • Reduce the number of validations you have to perform
  • Certificates of Compatibility available in the Resource Center



43481 20 x 90 mm



Assessment of prevalence and changing epidemiology of extended-spectrum beta-lactamase-producing Enterobacterales fecal carriers using a chromogenic medium

Paniagua R et al. Diagnostic Microbiology And Infectious Disease 2010;67:376-379

Performance of CHROMID ESBL, a chromogenic medium for detection of Enterobacterales producing extended-spectrum ß-lactamases

Réglier-Poupet H et al.Journal Of Medical Microbiology, 2008;57:310-315


ECCMID 2012 / London (United Kingdom)

A multi-center evaluation of 3 selective screening agars for the detection of extended-spectrum ß-lactamases

Floré K et al. ECCMID 2009 / Helsinki (Finland)

Evaluation of a chromogenic bioMérieux CHROMID ESBL medium for screening and presumptive identification of extended-spectrum ß-lactamase-producing Enterobacterales from surveillance cultures

Sánchez-Carrillo C et al.

Comparison of the CHROMID ESBL medium and MacConkey agar supplemented with ceftazdime (5mg/l) for the detection of extended-spectrum beta-lactamase producing Enterobacterales from rectal swabs in hospitals patients

Nonhoff C et al.

Please consult your local bioMérieux representative for product availability in your country

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