HIV Diagnostics & Management

Millions of people die each year from HIV/AIDS-related illnesses – 2/3 of them in Sub-Saharan Africa – despite medical and diagnostic advances. Accessible, flexible and high-quality testing is essential to help limit the spread of the disease and better manage HIV infection for improved prognosis and quality of life. On the frontlines against HIV from the beginning, bioMérieux is dedicated to making our best-in-class HIV solutions accessible and available to all, for better patient care everywhere.

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Truly global challenge

UNAIDS estimates that in 2015*:

 

  • 36.7 million people worldwide were living with HIV
  • 17 million people were living with HIV on antiretroviral therapy
  • 2.1 million people became newly-infected with HIV
  • 1.1 million people died from AIDS-related illnesses

*Source: AIDS by the numbers | UNAIDS | 2016

(http://www.unaids.org/en/resources/documents/2016/AIDS-by-the-numbers)

First identified in the 1980s, the human immunodeficiency virus (HIV), a lentivirus that targets white blood cells vital to the human immune system,1 has become a challenge of global proportions. It is transmitted through body fluids – most commonly through unprotected sexual contact. If left untreated, it leads to acquired immunodeficiency syndrome (AIDS) and ultimately death.

Medical advances have led to dramatically improved quality of life and prognosis for people living with HIV, although there is still no effective vaccine or cure. Good management of HIV is done through early detection and initiation of antiretroviral treatment (ART), along with ongoing screening to ensure the best-adapted therapies. However, access to these possibilities is not available equally to all people. That’s why expert organizations, such as the WHO, UNAIDS and the CDC, place a strategic focus on making HIV education, testing, screening and therapies accessible to all, in order to reduce the numbers of new HIV infections and improve quality of life for those living with the disease around the world.

The aim of the global Diagnostics Access Initiative is to achieve the ambitious, but achievable “90-90-90 treatment target” to lay the groundwork to end the AIDS epidemic as a public health threat by 2030.

The treatment target for 2020 is the following:

 

According to UNAIDS, optimizing the use of diagnostics will be critical to achieve this target.

 

bioMérieux solution: High quality, flexible, & accessible

  • High Quality HIV assay, platform and service contributes to improved patient outcomes
  • Accessible to patients and at-risk populations anywhere in the world
  • Flexible to suit the widest variety of testing needs and set-ups

bioMérieux developed one of the very first HIV screening tests available in 1985, not long after the discovery of the virus. Our goal is to make flexible, high quality HIV testing accessible to everyone, in all types of healthcare settings and systems.

  • For diagnostic testing, we offer ultra-sensitive combined 4th generation ELISA (enzyme-linked immunosorbent assay) and Advanced 4th generation tests. These tests simultaneously detect HIV antibodies and the HIV1 p24 antigen, enable effective detection earlier than antibody-only tests.2 Our VIDAS® HIV DUO ULTRA and VIDAS® HIV DUO Quick  tests detect HIV during primary infection (within 1-3 weeks), even before production of antibodies. Early diagnosis means being able to begin appropriate care faster. Antiretroviral treatments (ART) keep viral load down, lower the risk of transmission3,4 and lower the chance of developing AIDS2.  

 

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VIDAS®HIV DUO: rapid 4th generation tests

The easy to use VIDAS® HIV DUO tests offer excellent analytical sensitivity, low limit of detection of HIV infection and high p24 Ag sensitivity*.

 

*SOURCES: Ly TD, et al. 2007 Jul;143(1):86-94. Epub 2007, Mar 28.

Miedouge M, et al. J Clin Virol. 2011 Jan;50(1):57-60. doi: 10.1016/j.jcv.2010.09.003.

 

 

Experience and commitment

bioMérieux: a partner in HIV

“I am utterly convinced that the solution to global public health needs, and especially those relating to AIDS, is to be found in cross-disciplinary approaches involving scientists and public-private partnerships, combining industrial know-how with humanitarian concerns.”

-Alain Mérieux, founder of bioMérieux

Fighting HIV/AIDS requires a collaborative approach at the community, country and global level. At bioMérieux, we are committed to contributing to this approach through research, development, education, and social responsibility.

Our long experience at the forefront of the HIV/AIDS epidemic and our expertise in microbiology ensure we meet the needs of those providing frontline care as well as of public health bodies and NGOs engaged in the issue. That’s why we build a global offer that’s high-quality and takes into account the multiple facets of optimal prevention and care. We aim for flexibilty in our offer because we believe everyone has the right to HIV education, diagnosis and quality care. We are also aware that HIV/AIDS is inextricably linked to the other diseases that it leaves patients vulnerable to. Other bioMérieux product lines target many of these diseases: viral/bacterial/fungal infections, hepatitis, tuberculosis and malaria, among others.

In your daily combat against HIV/AIDS, you can count on bioMérieux as your long-term partner, providing quality diagnostic and screening tests to support optimal care worldwide.

 

References

1 Cunningham, A.; Donaghy, H.; Harman, A.; Kim, M.; Turville, S. (2010). "Manipulation of dendritic cell function by viruses". Current opinion in microbiology 13 (4): 524–529. doi:10.1016/j.mib.2010.06.002. PMID 20598938.

2 Moyer, VA. Annals of Internal Medicine Clinical Guidelines: Screening for HIV: U.S. Preventive Services Task Force Recommendation Statement. April 30, 2013

3 CDC. Proven Prevention Methods. June 2012.

4 WHO Global health sector strategy on HIV/AIDS, 2011-2015

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