MYCOPLASMA IST 3

Simple and complete diagnosis of urogenital mycoplasmas

MYCOPLASMA IST 3 combines enumeration, identification and antibiotic susceptibility testing for detection of Mycoplasma hominis and Ureaplasma spp. 

  • Complete diagnosis in one step
  • Simple, secure and convenient
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Complete diagnosis in one step

The increasing resistance of Ureaplasma spp. and M. hominis to current antibiotics requires the testing of new, better adapted antibiotics.

The MYCOPLASMA IST 3 strip enables the identification and enumeration of the Mycoplasma hominis and Ureaplasma spp. In addition, 6 antibiotics can be tested:

 

 

MYCOPLASMA IST 3

Ureaplasma spp.

Mycoplasma hominis

Erythromycin

+

-

Tetracycline

+

+

Telithromycin

+

-

Levofloxacin

+

+

Moxifloxacin

+

+

Clindamycin

-

+

Doxycycline

+ deduced

+ deduced

Azithromycin

+ deduced

-

New features and benefits 

EASILY SWITCH TO MYCOPLASMA IST 3
STATE-OF-THE-ART MYCOPLASMA TESTING FROM COLLECTION TO RESULTS

NEW FEATURES DIRECT BENEFITS
Validated on male urine and semen Less invasive collection for improved patient comfort
Compatible with ESwab® for urethral, vaginal and cervical swabs More applications
Includes all antibiotics recommended by the CLSI Optimized preanalytical step
Improved sensitivity: threshold of 103 CFU/mL for Ureaplasma spp. for urine Compliance with international guidelines
AST differenciated for mixed culture of Ureaplasma spp. and M. hominis Improved pathogen detection
Large and robust clinical trials Reliable guidance of antibiotherapy
Report in CFU/mL Result standardization

Our solution

Culture, identification, enumeration and antibiotic susceptibility tests:

  • MYCOPLASMA IST 3 – Ref. 422083
    25 tests: 25 strips of 25 tests + 25 R1 vials + 25 lyophilised R2 vials

Detection:

  • UREA-ARGININE LYO 2 BROTH – Ref. 42508
    25 tests (25 R1 vials + 25 lyophilized R2 vials)

Collection and culture:

  • ESwab® RANGE
    ESwab® 490CEA
    Tube + 1 regular FLOQSwab
  • ESwab® 491CEA
    Tube + 1 Mini tip FLOQSwab
  • MYCOPLASMA PREPARATION – Ref. 42507
    8 tests (8 R1 vials for specimen collection and transport)

 

Excellent performance

EVALUATION BY THREE
CLINICAL LABORATORIES
 
SAMPLES (n = 516)
Cardiff (UK)
• 45% vaginal/cervical swabs
Lyon (France)
• 11% urethral swabs
• Pancevo (Serbia)
• 17% semen
 
• 28% male urine

 

TEST 1: DETECTION AND IDENTIFICATION
  Positive Agreement Negative Agreement
At the sample level
97.5 [94.4-99.2]%
(199/204)
99.7 [98.2-100.0]%
(311/312)
At the species level
Ureaplasma spp.
98.5 [94.6-99.8]%
(129/131)
99.7 [98.6-100.0]%
(384/385)
At the species level
Mycoplasma hominis
92.6 [85.6-96.4]%
(88/95)
99.0 [97.5-99.7]%
(410/414)

 

TEST 2: INDICATIVE ENUMERATION
  Exact Agreement
Within ± 101 CFU/ml
Agreement
Combined species
86.0 [80.3;90.3]%
(160/186)
97.8 [94.6;99.4]%
(182/186)
At the species level
Ureaplasma spp.
86.3 [78.9-91.4]%
(101/117)
100.0 [96.9-100.0]%
(117/117)
At the species level
Mycoplasma hominis
83.7 [74.5-90.0]%
(72/86)
94.2 [87.1;97.5]%
(81/86)

 

TEST 3: ANTIMICROBIAL SUSCEPTIBILITY TESTING
Ureaplasma
spp.
Isolates status (BMD) Performance Index
  Total #S #R CA ME VME
Levofloxacin 124 120 4
96.0%
(119/124)
4.2%
(5/120)
0
Moxifloxacin 124 123 1
98.4%
(122/124)
1.6%
(2/123)
0
Tetracycline 124 120 1
97.6%
(121/124)
1.7%
(2/120)
1
Erythromycin 124 120 4
99.2%
(123/124)
0.8%
(1/120)
0
Telithromycin 125 120 3
99.2%
(124/125)
0.8%
(1/122)
0
All drugs combined 621 605 16
98.1%
(609/621)
1.8%
(11/605)
1
Mycoplasma hominis Isolates status (BMD) Performance Index
  Total #S #R CA ME VME
Levofloxacin 84 82 2
98.8%
(83/84)
1.2%
(1/82)
0
Moxifloxacin 84 81 3
97.6%
(82/84)
1.2%
(1/81)
1
Tetracycline 84 65 19
97.6%
(82/84)
1.5%
(1/65)
1
Clindamycin 84 84 0
100.0%
(84/84)
0.0%
(0/84)
N/A
All drugs combined 336 312 24
98.5%
(331/336)
1.0%
(3/312)
2
All drugs and
species combined
957 917 40
98.2%
(940/957)
1.5%
(14/917)
3

BMD : Broth MicroDilution / CA : Category Agreement / ME : Major Error / VME : Very Major Error

Please consult your local bioMérieux representative for product availability in your country

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